Occurrence and Risk Factors of Renal Artery Stenosis in Patients Undergoing Abdominal Computed Tomography Angiography, a One-Year Study in a Tertiary Hospital in Manila


Renal artery stenosis (RAS) is one of the most common primary diseases of the renal arteries. It is associated with hypertension as well as ischemic renal disease. Its concomitant presence constitutes a high cardiovascular risk, thus timely diagnosis is important. This study aims to determine the occurrence of RAS in patients undergoing abdominal CT angiography and determines other factors that predict the highest-risk subset who have significant renal artery narrowing. A retrospective review of records of 470 patients who underwent CT angiography of the whole abdomen was done. RAS occurs in about 9.57% of patients who had a CT scan of the whole abdomen. Older patients, patients with heart disease and patients with more atherosclerotic vessels in the abdomen increases the risk for significant RAS (p values of 0.005, 0.008 and <0.001, respectively). Diabetes, hypertension as well as other imaging findings such as the presence of aneurysm elsewhere seen in the abdominal scans and renal artery duplication do not statistically correlate with the increased risk for RAS in this study.

Keywords: renal artery stenosis, CT angiography, atherosclerosis, fibromuscular dysplasia, hypertension

  1. Granata A, Fiorini F, Andrulli S, Logias F, Gallieni M, Romano G, et al. Doppler ultrasound and renal artery stenosis: An overview. Journal of Ultrasound. 2009;12(4):133–43.
  2. Yamashita T, Ito F, Iwakiri N, Mitsuyama H, Fujii S, Kitabatake A. Prevalence and predictors of renal artery stenosis in patients undergoing cardiac catheterization. Hypertension Research. 2002;25(4):553–7.
  3. Aboyans V, Desormais I, Magne J, Morange G, Mohty D, Lacroix P. Renal artery stenosis in patients with peripheral artery disease: prevalence, risk factors and long-term prognosis. European Journal of Vascular and Endovascular Surgery. 2017;53(3):380–5.
  4. Harding MB, Smith LR, Himmelstein SI, Harrison K, Phillips HR, Schwab SJ, et al. Renal artery stenosis: prevalence and associated risk factors in patients undergoing routine cardiac catheterization. Journal of the American Society of Nephrology. 1992;2(11):1608–16.
  5. Al-Katib S, Shetty M, Jafri SM, Jafri SZ. Radiologic assessment of native renal vasculature: a multimodality review. RadioGraphics. 2017;37(1):136–56.
  6. Zoccali C. Atherosclerotic renal artery stenosis: epidemiology, cardiovascular outcomes, and clinical prediction rules. Journal of the American Society of Nephrology. 2002;13 Suppl 3:S179-83.
  7. Claudon M, Plouin PF, Baxter GM, Rohban T, Devos DM. Renal arteries in patients at risk of renal arterial stenosis: multicenter evaluation of the echo-enhancer SH U 508A at color and spectral Doppler US. Radiology. 2000;214(3):739–46.
  8. Gilfeather M, Yoon H, Siegelman ES, Axel L, Stolpen AH, Shlansky-Goldberg RD, et al. Renal artery stenosis: evaluation with conventional angiography versus gadolinium-enhanced MR angiography. Radiology. 1999;210(2):367–72.
  9. Ota H, Takase K, Rikimaru H, Tsuboi M, Yamada T, Sato A, et al. Quantitative vascular measurements in arterial occlusive disease. RadioGraphics. 2005;25(5):1141–58.
  10. Johnson PT, Halpern EJ, Kuszyk BS, Heath DG, Wechsler RJ, Nazarian LN, et al. Renal artery stenosis: CT angiography—comparison of real-time volume-rendering and maximum intensity projection algorithms. Radiology. 1999;211(2):337–43.
  11. Olin JW. Renal artery disease: diagnosis and management. Mt Sinai J Med. 2004;71(2):73–85. 
  12. Tafur JD, White CJ. Renal artery stenosis: when to revascularize in 2017. Current Problems in Cardiology. 2017;42(4), 110–35.
  13. Wachtell K1, Ibsen H, Olsen MH, Laybourn C, Christoffersen JK, Nørgaard H, et al. Prevalence of renal artery stenosis in patients with peripheral vascular disease and hypertension. J Hum Hypertens. 1996;10(2):83–5. 

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