Structure-Function Correlation of Juxtapapillary Choroidal Thickness With Visual Field Analysis of Patients Suspected With Glaucoma

Maria Katrina L. Malgapu, Celeste P. Guzman

May 2020 DOI 10.35460/2546-1621.2018-0125     Access   

Abstract

Purpose: To conduct an evaluation of juxtapapillary choroidal thickness of patients suspected with glaucoma obtained through spectral domain optical coherence tomography (SD-OCT) and correlate it with perimetry results.

Methods Design: Cross-sectional Study Population: 175 eyes diagnosed as “glaucoma suspect” had standard automated perimetry (SAP) to document the presence of functional glaucomatous damage using optimal near-point correction using the Humphrey Visual Field Analyzer II, 30-2 or 24-2 SITA-standard program. SD-OCT imaging of the retinal nerve fiber layer (RNFL) was also done to look for structural glaucomatous damage and in using enhanced depth imaging of the optic nerve and the Cirrus caliper tool, choroidal thickness was measured at five predetermined points temporal and nasal from the optic nerve. The population was classified into two groups: Group 1 are those with structural or functional glaucomatous damage (n=68) and Group 2 were those without (n=107).

Results: One-Way Multivariate Analysis of Covariance was used in comparing the mean temporal and nasal choroidal thickness scores of the two groups. There are no statistical differences in terms of the mean temporal choroidal thickness (p=0.856) and mean nasal choroidal thickness (p=0.734) between patients with and without glaucomatous damage. The mean temporal and nasal choroidal thickness scores of the two groups at different juxtapapillary locations: 0 μm, 250 μm, 500 μm, 750 μm and 1000 μm away from the disc were also not statistically different.

Conclusion: Results show that from this present cohort of glaucoma suspect patients, juxtapapillary choroidal thickness is not correlated with structural and functional glaucomatous damage.

Keywords: juxtapapillary choroidal thickness, glaucoma suspect, standard automated perimetry, spectral domain optical coherence tomography, enhanced depth imaging, retinal nerve fiber layer

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