Incidence of Contrast-induced Nephropathy in Patients Undergoing Coronary Angiography: An Annual Review in A University Hospital

Katherine Ann N. Tan, John Patrick F. Ona, Marcellus Francis L. Ramirez, Wilson L. Tan de Guzman

Apr 2018 DOI 10.35460/2546-1621.2017-0062     Access   

Abstract

Introduction: The rapidly growing number of percutaneous coronary interventions has led to a considerable improvement in the outcome of patients with acute coronary syndromes, yet concurrently exposing patients to enormous volumes of contrast media with the inherent risk of renal function impairment.

Objective: To determine the incidence of contrast induced nephropathy of patients admitted at University of Santo Tomas Hospital (USTH) who underwent coronary angiography with or without Percutaneous Transluminal Coronary Angioplasty (PTCA).

Methodology: This is a retrospective, descriptive study including patients aged 18 years and above, of any gender, admitted at the USTH from January 1, 2016 to December 31, 2016, who underwent coronary angiography with or without PTCA with baseline and follow up creatinine levels 48-72 hours after the procedure. Data were retrieved by review of medical records of these patients.

Results: Three out of 78 patients (3.8%) had elevated creatinine but all three patients also underwent major surgery within 48 hours after coronary angiography which could explain the renal impairment.

Conclusion: Although contrast induced nephropathy was described as the third most common cause of new Acute Kidney Injury in hospitalized patients, it was accordingly nil among those who underwent coronary angiography at USTH from January to December 2016. Benefits and risks of undergoing coronary angiography should always be weighed individually. Risk stratification scores should only serve as a guide in managing patients and proper preventive measures should be applied.

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DISCLOSURE AND CONFLICT OF INTEREST

The authors report no conflict of interest in this work

ACKNOWLEDGEMENT

The authors are grateful to all the participants of this study and to the University of Santo Tomas Hospital especially the Department of Medicine, Institutional Review Board (IRB) and Department of Medical Education and Research (DMER) who reviewed and approved this study.

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